In general, our studies have shown that these hormones are associated with acute perturbations in body fluid regulation such as altering the threshold for osmotically induced arginine vasopressin AVP, the primary hormone involved in the regulation of renal free water release and thirst onset, as well as alterations in the sodium-regulation hormones atrial natriuretic peptide ANP , renin, and aldosterone. The researchers asked the couples to start the timer as soon as vaginal penetration occurred, and stop the timer as soon as the man ejaculated. A series of studies described in this article used a newer paradigm to control the levels of sex hormones through the use of either a gonadotropin-releasing hormone GnRH agonist or antagonist Fig. The majority of men lasted between 4 to 11 minutes, with anyone lasting longer than 21 minutes being considered an outlier. Most of the historical data is hidden away in PDFs of these monthly reports, so I had the pleasure of scraping data from scans of dozens of CDC reports that were published 30 years before I was even born. One particularly confusing aspect of this data set was the fact that the post-war era in the s and s seemed to experience a significant drop in marriage rates, despite the fact that the s and s were known as a time of nearly-universal marriage in the U. In fact, when taking population into account, marriage rates in the U. To provide a more visual view of the data set, I charted the per capita marriage and divorce rates below, with a few annotations to denote major historical events.
Receptors for estrogens and progesterone are found in nonreproductive tissue involved in fluid regulation, such as the hypothalamus 10 , 21 , the cardiovascular system 6 , 19 , and the kidney tubules 6. This article will also address the potential impact of these sex hormones on plasma volume and fluid distribution within the extracellular fluid ECF space. Abstract In young women, estradiol and progesterone primarily control reproduction, but they also affect fluid regulation. Once the Baby Boomers came of age in the s, marriage rates returned to pre-WWII levels — barring a slight drop in marriages during the dramatic conclusion of the Vietnam War The study of reproductive hormone effects on physiological systems is complex in young women because of hormonal fluctuations over the course of the menstrual cycle Fig. For example, premenopausal women have delayed and less severe manifestation of cardiovascular diseases than do men 13 , and although there continues to be some controversy surrounding hormone replacement in postmenopausal women, hormone replacement therapy is usually associated with improved cardiovascular function in perimenopausal and postmenopausal women 6 , The majority of men lasted between 4 to 11 minutes, with anyone lasting longer than 21 minutes being considered an outlier. A series of studies described in this article used a newer paradigm to control the levels of sex hormones through the use of either a gonadotropin-releasing hormone GnRH agonist or antagonist Fig. After 4 weeks of stop watches and sex diaries, the researchers followed up with the couples to collect the diaries and ask them various demographic questions. To provide a more visual view of the data set, I charted the per capita marriage and divorce rates below, with a few annotations to denote major historical events. To provide a clearer view of the s and s, I plotted the raw counts for marriages and divorces below. So, there we have it. If you think you know why marriage rates have been declining in the U. To do so, they recruited about random heterosexual couples from The Netherlands, Spain, Turkey, the UK, and the US and asked them to track the duration of their sexual encounters using a timer and diary. The suppression is followed by controlled administration of estradiol, progesterone, or combined estradiol-progesterone to physiological levels. One mechanism by which estrogens or progesterone may impact physiological systems is through regulation of body fluids and sodium content. How long does the average man last in bed? Interestingly, the only notable spike in divorce rates in the past years also followed the conclusion of WWII, likely due to many of the pre-WWII marriages coming to an abrupt end once the romance of wartime marriage wore off. To provide a more succinct view of the data, I also created a box plot to summarize the distribution: One particularly confusing aspect of this data set was the fact that the post-war era in the s and s seemed to experience a significant drop in marriage rates, despite the fact that the s and s were known as a time of nearly-universal marriage in the U. Randy Olson Posted in data visualization A couple weeks ago, I ran across a research paper that inadvertently answered one of those awkward questions that so few people get the chance to talk about: Although total body water and sodium content are only mildly affected, data presented in this article suggest that reproductive hormones alter homeostatic set points for body fluid and tonicity. Most of the historical data is hidden away in PDFs of these monthly reports, so I had the pleasure of scraping data from scans of dozens of CDC reports that were published 30 years before I was even born. You see, these researchers were actually studying premature ejaculation. Moreover, the impact of sex hormones on body fluid and sodium regulation has important implications for a number of syndromes for which women are at risk, including orthostatic hypotension, insulin resistance, polycystic ovary syndrome, and neurological consequences from postoperative 8 and exercise-associated hyponatremia 1. Hopefully studies like this one will help us ground our expectations in reality, rather than trying to live up to fantasy.
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